Utah (Jack Kilmer) and Opal (Alice Englert) are junkies living on the streets of rural Ohio until a seemingly chance encounter with the enigmatic Wood (Michael Kenneth Williams) brings them to Los Angeles for drug treatment. Utah appears to find sobriety with the help of treatment center shrink, Dr. White (Melissa Leo), and tech turned love interest, May (Jessica Rothe). They soon learn that drug treatment is but a cover for a predatory business, enlisting addicts to recruit other addicts. Utah is no exception. Wood and his drug treatment mogul partner, Vin (Frank Grillo), take Utah under their wing, introducing him to the good life, though Utah's addiction remains his biggest obstacle.